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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FASN
All Species:
4.55
Human Site:
S279
Identified Species:
10
UniProt:
P49327
Number Species:
10
Phosphosite Substitution
Charge Score:
0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49327
NP_004095.4
2511
273427
S279
L
I
R
S
L
Y
Q
S
A
G
V
A
P
E
S
Chimpanzee
Pan troglodytes
XP_511758
2502
272092
X279
L
I
C
S
X
X
X
X
X
X
X
X
P
P
C
Rhesus Macaque
Macaca mulatta
XP_001113076
2516
273127
S279
L
I
R
S
L
Y
Q
S
A
G
V
A
P
E
S
Dog
Lupus familis
XP_540497
2473
268826
P279
L
I
R
S
L
Y
E
P
A
G
L
A
P
E
S
Cat
Felis silvestris
Mouse
Mus musculus
P19096
2504
272410
P279
L
I
C
S
L
Y
Q
P
A
G
L
A
P
E
S
Rat
Rattus norvegicus
P12785
2505
272631
P279
L
I
R
S
L
Y
Q
P
G
G
V
A
P
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P12276
2512
274763
E279
L
V
G
S
L
Y
R
E
C
G
I
K
P
G
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923643
2511
274126
E279
L
V
R
S
L
Y
Q
E
A
N
I
S
P
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137778
2544
278437
E423
L
I
R
E
T
Y
E
E
I
G
L
N
P
A
D
Honey Bee
Apis mellifera
XP_396268
2363
261441
E307
L
M
R
E
I
Y
A
E
A
G
I
N
P
A
D
Nematode Worm
Caenorhab. elegans
NP_492417
2613
289207
E315
L
L
Q
E
V
Y
S
E
A
G
I
D
P
N
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
92.8
80
N.A.
81.3
82
N.A.
N.A.
66.1
N.A.
64.3
N.A.
43.5
45
41.5
N.A.
Protein Similarity:
100
98.3
96.3
87.4
N.A.
90
90
N.A.
N.A.
80.2
N.A.
78.8
N.A.
61.3
63.6
60.6
N.A.
P-Site Identity:
100
26.6
100
80
N.A.
80
86.6
N.A.
N.A.
40
N.A.
60
N.A.
40
40
40
N.A.
P-Site Similarity:
100
26.6
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
60
N.A.
80
N.A.
53.3
60
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
64
0
0
46
0
19
0
% A
% Cys:
0
0
19
0
0
0
0
0
10
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
28
% D
% Glu:
0
0
0
28
0
0
19
46
0
0
0
0
0
55
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
10
82
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
64
0
0
10
0
0
0
10
0
37
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
100
10
0
0
64
0
0
0
0
0
28
0
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
19
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
28
0
0
0
0
100
10
0
% P
% Gln:
0
0
10
0
0
0
46
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
64
0
0
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
73
0
0
10
19
0
0
0
10
0
0
55
% S
% Thr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
19
0
0
10
0
0
0
0
0
28
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
91
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _